I am looking for advice for a new HP Z800 owner

For anyone out there with an HP Z series workstation who has made a hack out of it, what things should I do or look for?

Does it run Loud? Is a Quadro 4000 a decent card?

Its primary use is for PLEX and the occasional gaming like minrcraft and rocket league. It may end up being used for AutoCAD and other things eventually.

I am open to ANY tips from other owners.