Can I use XFX R9 270X on macOS Catalina?

Hi all, I'm using MacOS High Sierra on my PC without any problem. but now I want to have a cheap R9 270X to run macOS Catalina. Is there any problem so far or anything hard to fix when using the XFX R9 270X with lastest macOS?

P/s: Can I put 2 GPU, 1 from AMD, 1 from Nvidia on my motherboard then choose AMD to run on Hackintosh, and Nvidia to use with Windows?