What's the status of AMD vs. Nvidia in High Sierra?

I know there was hype with the Pascal web drivers, but I've also heard that the GTX 1060 has some sleep/wake problems at the moment.

I also remember that AMD cards required more hacking than the Nvidia cards and possibly the help of an iGPU to get started.

But with eGPU support in High Sierra and the new AMD cards in the iMacs, are AMD cards supported natively now? I'm thinking of the RX 580 specifically.